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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
drug:
Topotecan
supplement:
Serum Albumin, Human
Research Papers that Mention the Interaction
“11,12 Time-resolved fluorescence spectro- scopic investigations show that topotecan contains structural features which reduce binding of its carbox- ylate form to HSA ; 13 as a result, topotecan displays improved stabilities in human blood and plasma relative to camptothecin and 9-aminocamptothecin.”
Novel A,B,E-ring-modified camptothecins displaying high lipophilicity and markedly improved human blood stabilities.
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