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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Tolbutamide
supplement:
Phosphatidylinositol 4,5-Diphosphate
Research Papers that Mention the Interaction
“In addition to antagonizing high-affinity block by tolbutamide, PIP2 also altered the stimulatory action of the PCOs, diazoxide and MgADP.”
Sulfonylurea and K+-Channel Opener Sensitivity of KATP Channels“Ionomycin and tolbutamide promoted the rapid breakdown of PtdIns(4,5)P2 , whereas the breakdown of PtdIns4P was less rapid and of a lesser magnitude.”
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