supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
drug:
Tolbutamide
supplement:
Calcium Supplement
Research Papers that Mention the Interaction
“ Tolbutamide elicits an increase in [ Ca2+li in beta- and delta-cells, regardless of glucose concentrations.”
Different effects of tolbutamide and diazoxide in alpha, beta-, and delta-cells within intact islets of Langerhans.“ Tolbutamide diminishes the activity of Ca ,Mg-ATPase in native membranes by 25% without causing any appreciable influence on the enzyme activity in dephosphorylated membranes.”
“Addition of tolbutamide to a medium containing 6 mM glucose and calcium increased Rb+ efflux transiently with 20 micrograms/ml and permanently with 100 micrograms/ml.”
“In contrast to an analogue lacking effects on insulin release, tolbutamide stimulated the intracellular net uptake of 45 Ca as well as the efflux of the isotope.”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback