Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago

Possible Interaction: Tocophersolan and Berberine Hydrochloride

Research Papers that Mention the Interaction

TPGS at a concentration of 2.5% could improve peak concentration (Cmax) and area under the curve (AUC0–36) of BBR by 2.9 and 1.9 times, respectively.
The result showed that BBR had a very low absolute bioavailability of 0.68%, and TPGS could enhance intestinal absorption of BBR significantly.
This study indicated that absolute bioavailability of BBR was 0.68% in rats, and TPGS was a good absorption enhancer capable of enhancing intestinal absorption of BBR significantly.
AAPS PharmSciTech  •  2011  |  View Paper