“ TPGS at a concentration of 2.5% could improve peak concentration (Cmax) and area under the curve (AUC0–36) of BBR by 2.9 and 1.9 times, respectively.”
“The result showed that BBR had a very low absolute bioavailability of 0.68%, and TPGS could enhance intestinal absorption of BBR significantly.”
“This study indicated that absolute bioavailability of BBR was 0.68% in rats, and TPGS was a good absorption enhancer capable of enhancing intestinal absorption of BBR significantly.”