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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Tobramycin
supplement:
Resveratrol
Research Papers that Mention the Interaction
“Co-administration … concentrations of resveratrol increased the activity of aminoglycosides, … gentamicin, kanamycin, neomycin, streptomycin and tobramycin , up to 32-fold against S. aureus, while the effect was lower (2-4-fold reduction in … inhibitory concentration) for other Gram-positive pathogens (i.e. Staphylococcus epidermidis, Enterococcus faecium and Enterococcus faecalis).”
Resveratrol enhances the efficacy of aminoglycosides against Staphylococcus aureus.“These results indicate that the QSI resveratrol can significantly enhance the effects of aminoglycoside antibiotics (e.g. tobramycin , gentamicin, amikacin and netilmicin) on P. aeruginosa PAO1 biofilms.”
Can the quorum sensing inhibitor resveratrol function as an aminoglycoside antibiotic accelerant against Pseudomonas aeruginosa?
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