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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
supplement:
Vitamin C
Research Papers that Mention the Interaction
“ Vitamin C decreased plasma levels of fV (from 143 +/- 5.4 to 123 +/- 6.03%, … 133.5 +/- 14.5 to 109.5 +/- 11.4%, P = 0.016), and tPA (from 12.3 +/- 0.99 to 8.40 +/- 0.60 ….001), whereas these levels remained unaffected in the control group.”
Vitamin C affects thrombosis/ fibrinolysis system and reactive hyperemia in patients with type 2 diabetes and coronary artery disease.“Also, selectively in smokers, the maximal stimulated net release of t-PA antigen and of t-PA activity increased when ascorbic acid was infused simultaneously, P=0.002.”
“Latency to the removal of sticky labels from the forepaw was also significantly decreased after the administration of AA + r‐tPA (p < 0.05) at 24 or 48 hr after stroke.”
Ascorbic Acid Reduces the Adverse Effects of Delayed Administration of Tissue Plasminogen Activator in a Rat Stroke Model“Repetitive application of 0.16, 0.8, and 4.0 mumol AA with 5 nmol TPA inhibited tumor multiplicity by 16%, 46%, and 91%.”
“Repetitive application of 6 and 28 mumol AA with 2 nmol TPA inhibited tumor multiplicity by 39% and 76%.”
“Co-infusion of vitamin C induced greater tPA release in short sleepers.”
Negative Influence of Insufficient Sleep on Endothelial Vasodilator and Fibrinolytic Function in Hypertensive Adults.“The results show that ascorbic acid could inhibit 5.5% to 97.1% of transformation of JB6 P+ cell Cl 41-19 induced by TPA , EGF or EGF + insulin, but has no effect on anchorage-independent growth of JB6 transformed cell A33.”
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