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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Tissue Plasminogen Activator and Quercetin

Research Papers that Mention the Interaction

Our data indicate that quercetin modulates the release of ET-1, t-PA , and PGI2 from vascular endothelial cells.
Journal of ethnopharmacology  •  1999  |  View Paper
Among flavonoids, quercetin resulted in effective inhibition of EA induction by TPA and alpha-naphthoflavone showed the weakly inhibitory effect.
Cancer letters  •  1983  |  View Paper
The activation of activator protein-1 and nuclear factor-kappaB induced by TPA was dose dependently inhibited by RWE or quercetin treatment.
Cancer research  •  2008  |  View Paper
Painting of 0.6 mumol of 1-phenyl-2-pyrazolidone, 8.2 nmol of salcophytol A, 17 … of retinoic acid, 5.6 mumol of 3(2)-tert-butyl-4-hydroxyanisol, and 3 mumol of quercetin 45 min before each TPA treatment decreased the suppressive effect on the footpad reaction.
Chemical & pharmaceutical bulletin  •  1992  |  View Paper
These findings suggest that quercetin inhibits or compensates a common effect induced by both TPA and DDT.
Carcinogenesis  •  1987  |  View Paper
Quercetin at a low concentration (5 micrograms/ml) markedly suppressed the promoting action of 12-O-tetradecanoyl phorbol-13-acetate ( TPA , 10 ng/ml) in this transformation system using 20-methylcholanthrene (MCA, 1 microgram/ml) as the initiator.
Japanese journal of cancer research : Gann  •  1987  |  View Paper