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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Masoprocol
Research Papers that Mention the Interaction
“It was found that CsA‐resistant proliferative responses induced by direct PK‐C activators such as mitogenic concentrations of the phorbol ester TPA or the putative anti‐tumour agent bryostatin 1 (bryo 1) were inhibited in a concentration‐dependent manner by NDGA (IC50 = 2 μM).”
Nordihydroguaiaretic Acid Blocks IL‐2‐Independent Lymphocyte Proliferation and Enhances Responses to PPD“However, nordihydroguaiaretic acid , which blocks cyclooxygenase and lipoxygenases, potentiated the effect of TPA on proenkephalin mRNA, when used at concentrations of 0.5-50 mumol/l.”
Evidence for the involvement of 5-lipoxygenase products in the regulation of the expression of the proenkephalin gene in cultured astroglial cells.“ Nordihydroguaiaretic acid (NDGA), a lipoxygenase inhibitor, abolished both the TPA and prolactin effects on [3H]uridine incorporation.”
“Treatment of mice with nordihydroguaiaretic acid (10 to 90 mumol/mouse), a lipoxygenase inhibitor, also inhibited the induction of ODC by TPA.”
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