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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
supplement:
Epigallocatechin Gallate
Research Papers that Mention the Interaction
“ Tea catechins also suppressed TPA (12-O-tetradecanoylphorbol-13-acetate)-induced inflammation, and the tendency of the pol inhibitory activity was the same as that of anti-inflammation.”
Structural analysis of catechin derivatives as mammalian DNA polymerase inhibitors.“Although EGCG did not directly inhibit the production of GM-CSF, it did inhibit the effect of TNF-alpha or TPA , both of which stimulated AML cells to produce GM-CSF.”
“On analysis of PKC activity with partial purified preparation, TPA (100 ng/mL) treatment was able to elevate membrane-associated PKC activity approximately 3-fold, and treatment with TF-3 (20 microM) and EGCG (20 microM) showed 94.5% and 9.4% suppression on TPA-induced PKC activity, respectively.”
Inhibition of TPA-induced protein kinase C and transcription activator protein-1 binding activities by theaflavin-3,3'-digallate from black tea in NIH3T3 cells.“Topical application of EGCG (1 or 5 mumol) one hour before the application of TPA inhibited all TPA-induced gene expression in a dose-dependent fashion.”
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