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Discover Supplement-Drug Interactions

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Last Updated: 4 months ago

Possible Interaction: Timolol and Vitamin E

drug:

Timolol

supplement:

Vitamin E

Research Papers that Mention the Interaction

A 20% vitamin E loading was found to increase the release time of timolol and levofloxacin by a factor of 5 and 3-fold respectively, but this increase proved much less effective compared to vitamin E's effect on other commercial silicone hydrogels.
International journal of pharmaceutics  •  2017  |  View Paper
Loading of vitamin E to pHEMA-hydrogel contact lenses significantly increased the loading of a hydrophilic drug surrogate (Alexa Fluor 488 dye) and two hydrophilic glaucoma drugs ( timolol and brimonidine) to the lenses by 37.5%, 19.1%, and 18.7%, respectively.
Scientific reports  •  2016  |  View Paper
Loadings of 10 and 40% Vitamin E increase release time of timolol by a factor of about 5 and 400, respectively for NIGHT&DAY lens.
Biomaterials  •  2010  |  View Paper