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Discover Supplement-Drug Interactions

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Last Updated: 3 months ago

Possible Interaction: Tibolone and Soy Isoflavones

supplement:

Soy Isoflavones

Research Papers that Mention the Interaction

Tibolone is often taken concurrently with soy.
Climacteric : the journal of the International Menopause Society  •  2008  |  View Paper
In postmenopausal women using tibolone, soy reduced plasma LDL-C concentrations by approximately 10% from baseline without a change in HDL-C. CONCLUSIONS Co-administration of soy during tibolone treatment improved the lipoprotein profile in both monkeys and women; however, the effects were more robust in monkeys.
RESULTS Monkeys given Tib alone had approximately 14% increase in plasma LDL + VLDL-C; whereas those given soy combined with tibolone had significant ( approximately 22%) reductions.
Maturitas  •  2008  |  View Paper