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Last Updated: 6 months ago

Possible Interaction: Thyroxine and Lithium Carbonate

Research Papers that Mention the Interaction

Lithium carbonate in a dose of 900-1800 mg daily during 4-6 weeks produced a significant reduction in T3 level; the level of T4 was less reduced, and the TTH concentration increased.
Problemy endokrinologii  •  1982  |  View Paper
A significant decrease in T4 and TTH levels in the hemocirculation was observed in thyrotoxicosis patients under the influence of lithium carbonate prompting the return of disturbed myocardial function to normal and rapid restoration of microcirculatory disorders (the isotonic nature of cardiac activity turned into isometric).
Meditsinskaia radiologiia  •  1986  |  View Paper
The administration of lithium carbonate produced a slowing of thyroxine disappearance in all hyperthyroid subjects, but had no effect in euthyroid patients.
The Journal of clinical endocrinology and metabolism  •  1973  |  View Paper
Serum triiodothyronine (T3) and T4 by radioimmunoassay showed that PTU alone and in combination with Li lowered serum T4, while a high level of T4 by its supplement was suppressed by co-administration of Li.
Journal of pharmacobio-dynamics  •  1989  |  View Paper