supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago
drug:
Thyroxine
supplement:
Calcium Acetate
Research Papers that Mention the Interaction
“A decrease in the absorption of LT4 is established and clinically significant when administered concomitantly with cholestyramine, colesevelam, lanthanum, calcium carbonate, calcium citrate, calcium acetate , iron sulfate, ciprofloxacin, aluminum hydroxide, sevelamer, or proton pump inhibitors.”
Factors Affecting Gastrointestinal Absorption of Levothyroxine: A Review.“Sevelamer was also found to be associated with significantly higher dosing requirement of thyroid replacement than those on either calcium carbonate or calcium acetate (Z = −3.17, P = 0.001).ConclusionSevelamer (but not calcium acetate ) in addition to calcium carbonate appears to interfere with the bioavailability of levothyroxine.”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback