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Last Updated: 2 years ago

Possible Interaction: Thyrotropin-Releasing Hormone and Yohimbine

Research Papers that Mention the Interaction

The behavioural excitation caused by TRH was antagonized by pretreatment of the rats with either a narcotic receptor antagonist, naloxone, an alpha-adrenergic receptor antagonists, yohimbine , or a dopaminergic receptor antagonist, haloperidol, but not with a beta-adrenergic receptor antagonist, propranolol.
Neuropharmacology  •  1983  |  View Paper
Furthermore, the fever induced by intrahypothalamic administration of TRH was greatly reduced by pretreatment with intrahypothalamic administration of either yohimbine (a blocking agent of alpha-adrenergic receptors), phentolamine (a blocking agent of alpha-adrenergic receptors) or DL-propranolol (a blocking agent of beta-adrenergic receptors) in the rat.
Journal of Neural Transmission  •  2005  |  View Paper
The locomotor stimulant action provoked by TRH was antagonized by pretreatment of ventromedial hypothalamus with either an alpha-adrenergic receptor antagonist ( yohimbine ), a dopaminergic receptor antagonist (haloperidol) or an opiate receptor antagonist (naloxone), but not with a beta-adrenergic receptor antagonist (propranolol).
Journal of Neural Transmission  •  2005  |  View Paper
The increased gastric acid secretion and contraction in response to TRH were significantly augmented by pretreatment with yohimbine but not with prazosin.
Japanese journal of pharmacology  •  1995  |  View Paper
Pretreament with yohimbine reduced total cerebral blood flow moderately and in such animals thyrotropin-releasing hormone elicited only minor cerebral blood flow effects.
Acta physiologica Scandinavica  •  1991  |  View Paper
The TRH "Roche"-induced hyperglucagonemia was inhibited by phentolamine (an alpha-receptor blocking drug), yohimbine (an alpha-2 -receptor blocking drug) and atropine.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme  •  1985  |  View Paper