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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Thyrotropin-Releasing Hormone and Tyrosine

Research Papers that Mention the Interaction

Alternatively, TRH inhibited PKC activity by reducing the EGF receptor serine/threonine phosphorylation, thereby enhancing tyrosine phosphorylation.
American journal of physiology. Endocrinology and metabolism  •  2006  |  View Paper
TRH has been found to stimulate tyrosine phosphorylation of the epidermal growth factor (EGF) receptor.
Molecular endocrinology  •  2000  |  View Paper
We showed that tyrosine at position 106 in transmembrane helix 3 of the TRH receptor directly binds the ring carbonyl of the pyroglutamyl moiety of TRH (Perlman, J. H., Thaw, C. N., Laakkonen L., Bowers, C. Y., Osman, R., and Gershengorn, M. C. (1994) J. Biol.
The Journal of biological chemistry  •  1994  |  View Paper
Recently we have found that TRH stimulates early tyrosine phosphorylation of MAP kinase in GH3 cells.
Biochemical and biophysical research communications  •  1994  |  View Paper
TRH stimulated the tyrosine phosphorylation of the 52-kDa Shc protein, although neither phorbol esters nor the calcium ionophore A23187 had any effect, indicating that this effect of TRH was not dependent on PKC.
The Journal of biological chemistry  •  1994  |  View Paper