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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Tretinoin
Research Papers that Mention the Interaction
“According to these in vitro results, several papers reported that the … in vivo to euthyroid or hypothyroid rats of pharmacological amounts of retinoic acid , an active metabolite of vitamin A, reduces both basal and thyrotropin-releasing hormone (TRH)stimulated TSH secretion, independently of the thyroid status of the animals.”
Treatment with retinoid X receptorgamma-selective ligand (bexarotene) may cause iatrogenic central hypothyroidism.“Expression of 61 TRF genes was significantly changed during ATRA incubation, providing many potential regulatory edges.”
“Similarly, RA administration to hypothyroid rats led to a decrease on TSH responses to TRH.”
“We found that rats treated with RA showed a decrease in spontaneous basal TSH levels and TSH responses to TRH.”
Retinoic acid inhibits in vivo thyroid-stimulating hormone secretion.
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