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“In conclusion, thymol suppressed cardiac ionic channels in a concentration‐dependent manner, however, both drug‐sensitivities as well as the mechanism of action seems to be different when blocking calcium and potassium channels.”
British journal of pharmacology • 2002 | View Paper
“KEY FINDINGS Th mol si gnificantly reduced the elevated serum levels of colon related tumor markers carbohydrate antigen 19-9 (CA 19 -9) and carcinoembryonic antigen (CEA) as well as the apoptotic marker, caspase-3 compared with the colon cancer group.”
Natural product communications • 2009 | View Paper
“It is shown that the amount of calcium accumulated in FSR is determined by the balance between the rapid influx and efflux of calcium, and that both processes are depressed by thymol.”
“The mechanism was studied of the overshoot of calcium accumulation in … sarcoplasmic reticulum (FSR) which is observed when the active transport of calcium into FSR is performed … the presence of thymol ; the amount of calcium in FSR increases steeply during … first minute of the reaction and then decreases markedly.”