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Discover Supplement-Drug Interactions

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Possible Interaction: Threonine and Vitamin B 6




Vitamin B 6

Research Papers that Mention the Interaction

One possible explanation for the change in value of the activity ratio is that serine and threonine affect differently the binding of pyridoxal 5′-phosphate, thus altering differently the balance between the amount of active holoenzyme and inactive apoenzyme in the reaction systems.
European journal of biochemistry  •  1972  |  View Paper
However, at pH 7.2, the addition of pyridoxal phosphate leads to a tripling of the small activity toward l-threonine.
The Journal of biological chemistry  •  1968  |  View Paper
This observation constitutes the first direct evidence in support of the view that 4‐hydroxy‐l‐threonine is implicated in the biosynthesis of vitamin B6.
FEBS letters  •  1993  |  View Paper
Incubation of dehydratase with L-threonine shifted the absorption maximum of the enzyme-bound pyridoxal phosphate from 413 to 425 nm; addition of glyoxylate completely prevented the threonine-mediated spectral shift.
The Journal of biological chemistry  •  1979  |  View Paper
l-Serine O-sulphate and l-threonine O-sulphate are degraded in the presence of pyridoxal 5'-phosphate to yield equimolar amounts of the corresponding keto acid, ammonia and sulphate.
The Biochemical journal  •  1968  |  View Paper