Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 months ago

Possible Interaction: Threonine and Tyrosine

supplement:

Threonine

supplement:

Tyrosine

Research Papers that Mention the Interaction

Phosphorylation on tyrosine and O-GlcNAcylation on nearby serine or threonine residues may modulate each other.
Amino Acids  •  2019  |  View Paper
Substitution of threonine with tyrosine or phenylalanine alone confers decreased susceptibility to the inhibitor.
Journal of virology  •  1994  |  View Paper
Removing CH from the plasma membrane increased tyrosine and threonine phosphorylation of occludin, and transepithelial electrical resistance (TER) within 30 min.
Experimental cell research  •  2007  |  View Paper
By the supplementation of both methionine and threonine to the high tyrosine diet , the enhancement of brain tyrosine and MHPG-SO4 caused by tyrosine was significantly reduced.
The supplemented methionine and threonine may cause an increase of tyrosine utilization, because methionine and threonine are the most limiting amino acids in casein, and also may inhibit the uptake of tyrosine into the brain via the blood-brain barrier.
Journal of nutritional science and vitaminology  •  1985  |  View Paper
Tyrosine exerted a significant stimulating effect on the absorption of most amino acids absorbed from the caecum, e.g. Asp-NH2, Ser, Thr , Arg, Asp, Glu.
Acta physiologica Polonica  •  1978  |  View Paper
An increased blood tyrosine level in rats fed excess tyrosine was also lowered by threonine supplementation.
The Journal of nutrition  •  1977  |  View Paper
Equimolar combinations of LYS plus THR were inhibitory at both 0.1 and 0.5 mM. Incorporation of [14C] aspartic acid (ASP) and [3H]tyrosine ( TYR ) was also reduced by 1 mM LYS or THR.
Planta  •  2004  |  View Paper