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Discover Supplement-Drug Interactions

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Last Updated: 2 months ago

Possible Interaction: Threonine and Tryptophan

supplement:

Threonine

supplement:

Tryptophan

Research Papers that Mention the Interaction

Generally, Trp addition linearly increased gain and feed intake at a Thr :Lys ratio of 0.60 and 0.65 but not at a Thr:Lys ratio of 0.55.
Journal of animal physiology and animal nutrition  •  2005  |  View Paper
High level of L-threonine , L-alpha-alanine, L-valine (100 mM) considerably inhibit the accumulation of L-tryptophan from 0.24 or 2.40 mM solution, the highest inhibition (78-96%) being related to the sodium-dependent transport mechanism.
Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova  •  1986  |  View Paper
Since supplementation with threonine prevents the accumulation of fat in the livers … per cent casein basal diet (1, 3), and since the inclusion of tryptophan … threonine under certain conditions (5), an attempt has also been made to determine … the effects of these two amino acids and that of methionine.
The Journal of biological chemistry  •  1954  |  View Paper
The internal tryptophan concentration increases during the period of indole excretion, suggesting that threonine acts by increasing the activity of the tryptophan pathway.
Journal of bacteriology  •  1971  |  View Paper