Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
“IR-inducible phosphorylation of threonine 691 and serine 717 is also dependent on ATM and is more strongly impaired when both ATM and ATR are knocked down.”
Molecular and Cellular Biology • 2006 | View Paper
“ ATM phosphorylates Chk2 on threonine 68 , which promotes oligomerization and phosphorylation on threonines 383 and 387 within the activation loop of the catalytic domain.”