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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Threonine
drug:
Aldesleukin
Research Papers that Mention the Interaction
“Furthermore, supplement of the alanine tRNA or threonine tRNA increased IL-2 productivity of IL-2 HL.”
Optimization protein productivity of human interleukin-2 through codon usage, gene copy number and intracellular tRNA concentration in CHO cells.“Significance: IL-2Rβ threonine phosphorylation governs IL-2 signal transduction and may play a role in immune cell dysfunction.”
“CD3 and CD28 costimulation induced a complex response including decreased threonine phosphorylation in the ERK1 and ERK2 activation loops and increased phosphorylation of selected tyrosine sites on ERK1/2, p38, phospholipase C-γ, Src homology 2 domain-containing transforming protein 1, Grap2, and Vav-1, potentiating T cell activation.”
“Stimulation of human CD4+ T cell lines with interleukin 2 (IL-2) induces tyrosine, serine and threonine phosphorylation of a series of proteins involved in the IL-2 receptor (IL-2R) signaling pathway.”
“Expressions of ileal IL-2 , IL-6, IL-1β mRNA decreased with increasing Thr level (p < 0.05).”
Effect of dietary threonine on laying performance and intestinal immunity of laying hens fed low‐crude‐protein diets during the peak production period
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