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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Thiouracil
supplement:
Tyrosine
Research Papers that Mention the Interaction
“At a concentration of 0.5 mM, TU was found to totally inhibit melanin formation by tyrosinase catalyzed oxidation of 0.25 mM tyrosine in phosphate buffer at pH 6.8.”
Selective uptake of 2-thiouracil into melanin-producing systems depends on chemical binding to enzymically generated dopaquinone.“There is no doubt that the primary action of propjdthiouracil PTU ) and other drugs of the thiocarbamide series on the thyroid is an interference with the iodination of tyrosine.”
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