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Possible Interaction: Thiamine and Vitamin C




Vitamin C

Research Papers that Mention the Interaction

In addition, emerging evidence suggests that the combination of vitamin C , corticosteroids and thiamine may act synergistically to reverse sepsis induced organ dysfunction.
Pharmacology & therapeutics  •  2018  |  View Paper
As with acetaldehyde, pretreatment with high oral doses ofl-ascorbic acid ,l-cysteine, and a combination of these protectants in reduced amounts with thiamin gave a high degree of protection against lethal doses of acrolein.
Agents and Actions  •  2005  |  View Paper
Combining intravenous vitamin C with corticosteroids and thiamine reduced mortality by 31.9% in a beforeand-after cohort.
Chest  •  2017  |  View Paper
vitamin C (OR = 0.2, for the highest versus the lowest intake quintile; 95% CI: 0.2–0.4), β-carotene (… = 0.4; 95% CI: 0.2–0.5), folic acid (OR = 0.4; 95% CI: 0.2–0.6), thiamin (OR = 0.4; 95% …: 0.4–0.9).
Cancer Causes & Control  •  2004  |  View Paper
In conclusion, ascorbic acid combined with thiamine exhibited protective effect on reproductive system by inhibiting Pb-induced excessive cell apoptosis.
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban  •  2009  |  View Paper
However, simultaneous supplementation of ascorbic acid and thiamine at the highest dose promoted testicular cell apoptosis via increased expressions of TGFbeta1 and caspase-3.
We explored the mechanism and examine the impacts of combined administration of ascorbic acid and thiamine at different levels on apoptosis in the testes of lead-exposed mice.
Clinica chimica acta; international journal of clinical chemistry  •  2006  |  View Paper
Ascorbic acid at 0.02--0.1 mM increased the thiamine diphosphatase activity by 20--600% and produced a significant amount of lipid peroxide, which was measured with thiobarbiturate under the same conditions as the enzyme.
Biochimica et biophysica acta  •  1979  |  View Paper
Observations on the synergistic action of thiamine and ascorbic acid were made as far back as 1939 when Kasahara and his co-workers injected ascorbic acid and thiamine subcutaneously into young rats and obtained a growth enhancement.
On the other hand, at least thiamine , pantothenic acid, and riboflavin were believed to stimulate independently the synthesis of ascorbic acid in some tissues.
Annals of the New York Academy of Sciences  •  1961  |  View Paper
As adverse effect, ascorbic acid may cause oxalate accumulation in the kidneys that can be prevented with the concomitant use of thiamine.
Critical Care  •  2020  |  View Paper
Although the positive results of the CITRIS-ALI study on mortality question the necessity of co-administration of hydrocortisone and thiamine when vitamin C is dosed sufficiently high, notably 66% of patients in CITRIS-ALI study received corticosteroids.
Critical Care  •  2019  |  View Paper
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