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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Thiamine
drug:
Trimethoprim
Research Papers that Mention the Interaction
“Further studies with drugs containing a 2,4-diaminopyrimidine resulted in the discovery that the antibiotic trimethoprim also potently inhibits thiamine uptake mediated by THTR-1 (IC50 = 6.84 µM) and THTR-2 (IC50 = 5.56 µM).”
Interaction of 2,4-Diaminopyrimidine–Containing Drugs Including Fedratinib and Trimethoprim with Thiamine Transporters
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