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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Thiamine and Trimethoprim

supplement:

Thiamine

Research Papers that Mention the Interaction

Further studies with drugs containing a 2,4-diaminopyrimidine resulted in the discovery that the antibiotic trimethoprim also potently inhibits thiamine uptake mediated by THTR-1 (IC50 = 6.84 µM) and THTR-2 (IC50 = 5.56 µM).
Drug Metabolism and Disposition  •  2017  |  View Paper