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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Thiamine Pyrophosphate
drug:
Aspartate
Research Papers that Mention the Interaction
“Mutating Glu89 to glutamine, aspartate and alanine markedly reduces catalytic activity and the affinity for ThDP , consistent with a role as the catalytic glutamate.”
Identification of the catalytic glutamate in the E1 component of human pyruvate dehydrogenase“A simultaneous administration of vitamin-coenzyme complex thiamine pyrophosphate , lipoate, sodium 4-phospho-pantothenate, flavin-mononucleotide, nicotinate) intensifies these metabolic shifts and protective action of L-aspartate.”
[The role of transaminases in realizing the protective effect of L-aspartate in hypoxia].“Simultaneous (together with L-… (pentapyruvate) which includes thiamine pyrophosphate , lipoate, sodium 4-phosphopantotenate, nicotinate and riboflavin-mononucleotide and stimulates the function … cycle to animals has induced intensification of the protective effect of L-aspartate and evoked further activation of the L-aspartate …, preagonal stages of the developing pathological state.”
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