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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Thiamine
supplement:
Alpha-Ketoglutaric Acid
Research Papers that Mention the Interaction
“In mitochondria from spontaneous mammary carcinoma which have a thiamine diphosphate level comparable with that of muscle mitochondria from newborn rats, addition of thiamine diphosphate causes a small but distinct rise in the oxidation rate of pyruvate and α-ketoglutarate.”
Thiamine diphosphate in growing tissues. IV. Pyruvate oxidation in muscle mitochondria from young rats and in mitochondria from malignant tissues.“KGA is no longer oxidized in the TCA cycle, because thiamine limitation inhibits α-ketoglutarate dehydrogenase.”
Biosynthesis of pyruvic acid from glucose by Blastobotrys adeninivorans
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