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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Theophylline
supplement:
Yohimbine
Research Papers that Mention the Interaction
“Micromolar concentrations of verapamil and yohimbine also reduced secretion, while the effect of theophylline was 100 times weaker.”
ATP-secretion occurs as an initial response in collagen induced platelet activation.“ Yohimbine (0.5 mg/kg), an a 2-adrenoceptor antagonist, diminished the antinociception of a single dose (75 mg/kg) of theophylline , whereas prazocin, an a 1-adrenoceptor antagonist, did not affect it.”
Effects of single and long-term theophylline treatment on the threshold of mechanical nociception: contribution of adenosine A1 and alpha2-adrenoceptors.“The …, 8‐phenyltheophylline (10 μM) and 8‐cyclopentyl‐1,3‐dipropylxanthine (0.1 μM), increased the amplitude of e.j.ps … 20 stimuli at 1 Hz in the presence, but not in the absence, of the α2‐adrenoceptor antagonist, yohimbine (1 μM) or the non‐… antagonist, phentolamine (1 μM).”
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