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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Theophylline
supplement:
Ipriflavone
Research Papers that Mention the Interaction
“Reduction of theophylline metabolism and elimination were observed in a theophylline‐treated patient during ipriflavone administration.”
Ipriflavone as an inhibitor of human cytochrome P450 enzymes“Results indicate that the reduction of theophylline clearance by concomitant ipriflavone administration observed by Takahashi et al. [Takahashi J., Kawakatsu K., Wakayama T., Sawaoka H. (1992): Elevation of serum theophylline levels by ipriflavone in a patient with chronic obstructive pulmonary disease.”
“Aniline hydroxylation activity of CYP2E1 was induced by theophylline + ipriflavone (100 mg/kg) coadministration as well.”
Interaction of theophylline and ipriflavone at the cytochrome P450 level
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