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Last Updated: 2 years ago

Possible Interaction: Tetrodotoxin and Cd2+

supplement:

Cd2+

Research Papers that Mention the Interaction

ICa TTX was suppressed by Na+ channel inhibitors such as TTX (10 microM) and Cd2+ (20 microM) and its decay was slowed by the specific Na+ channel activator veratrine (200 micrograms/ml).
Receptors & channels  •  1995  |  View Paper
These HT action potentials remained during the application of tetrodotoxin (600 nM), were blocked by Cd2+ (50 &mgr;M), and disappeared after superfusion with an extracellular solution deprived of Ca2+.
Anesthesia and analgesia  •  2016  |  View Paper
In the presence of tetrodotoxin DPs are voltage dependent and are depressed by Cd2+ and Co2+.
The Journal of physiology  •  1996  |  View Paper
Low‐threshold potentials persisted in TTX (1‐3 microM) but were blocked by solutions containing low Ca2+ (0.2 mM) and Cd2+ (0.5 mM), suggesting they were Ca(2+)‐dependent.
The Journal of physiology  •  1991  |  View Paper
In spontaneously firing neurons of the guinea pig substantia nigra pars compacta (SNC) maintained in slices, blockade of the fast spikes by tetrodotoxin (TTX) revealed a slow oscillatory potential change, which was depressed by Cd2+ , a Ca2+-channel blocker.
Neuroscience Letters  •  1989  |  View Paper
2 Tetrodotoxin , procaine, cysteine and glycerol pretreatment abolished these stimulatory effects of Cd2+.
British journal of pharmacology  •  1985  |  View Paper