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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Tetrahydrocannabinol (THC) and Tyrosine

Research Papers that Mention the Interaction

Our data suggest that blockade by THC of tyrosine phosphorylation of STAT1 alpha may be an important mechanism involved in the broad immunosuppressive effects of THC.
Biochemical pharmacology  •  1996  |  View Paper
Prolonged treatment of macrophages with THC resulted in a broad suppression of tyrosine phosphorylation and some cellular protein expression.
The data suggest that suppression of tyrosine phosphorylation by THC in macrophages may be one of the mechanisms associated with inhibition of cell function, including the suppression of tumor necrosis factor-alpha release from macrophages.
Biochemical pharmacology  •  1994  |  View Paper
THC also inhibited the active uptake of TYR into synaptosomes in all preparations studied.
THC produced increases in the conversion of TYR to DA in both preparations.
The Journal of pharmacology and experimental therapeutics  •  1982  |  View Paper