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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Tetrahydrocannabinol (THC) and Serum Albumin, Human

Research Papers that Mention the Interaction

Moreover, THC increases the affinity of heme for HSA.
Possibly, the HSA conformational transition(s) induced by THC binding could account for drug delivery to the liver through receptor‐ mediated endocytosis.
THC binds to two different binding sites of HSA (Kd1 ≤ 10−7 M and Kd2= 10−3 M) without affecting diazepam binding (Kd = 1.2 × 10−5 M).
IUBMB life  •  2011  |  View Paper