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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Tetracycline
supplement:
Sodium Bicarbonate
Research Papers that Mention the Interaction
“The present study shows that tetracycline absorption can also be reduced to a similar extent by sodium bicarbonate , an antaCid which contains no polyvalent cations and cannot form chelates with tetracycline.”
Decrease of tetracycline absorption in man by sodium bicarbonate“It is of interest that the absorption of tetracycline has recently been shown to be decreased by concurrent therapy with antacids in the absence of chelation.1In this instance, depressed blood levels of tetracycline were noted when the antibiotic was administered with sodium bicarbonate.”
“Patients receiving 250-mg capsules of tetracycline and 2.0 gm of sodium bicarbonate concomitantly were compared to patients receiving tetracycline alone.”
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