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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Tetracycline
supplement:
Calcium Supplement
Research Papers that Mention the Interaction
“Consequently the action of a drug may be … affected by magnesium (e.g., magnesium, calcium , and zinc can interfere with the gastrointestinal absorption of tetracycline antibiotics ) and simultaneously the physiological function of minerals such as magnesium may be impaired by a drug (e.g., diuretics induce renal magnesium loss).”
Magnesium and Drugs“Milk and other sources of calcium inhibit absorption of tetracycline.”
“ Calcium ions in plasma appeared to reduce tetracycline uptake by the red cells.”
“■ This supplement should be taken at least 2 hours apart from prescription medications as both fiber and calcium can affect absorption of certain medications, particularly tetracycline and floroquinolone antibiotics, levothyroxine, and digoxin.”
“It is well established that the bioavailability of tetracycline can be decreased through the concomitant administration of calcium and bismuth salts.5,6 Whether gastrointestinal chelation significantly alters the antiHelicobacter activity of these luminally acting agents is not as well understood.”
“It is well established that the bioavailability of tetracycline can be decreased through the concomitant administration of calcium and bismuth salts.5,6 Whether gastrointestinal chelation significantly alters the antiHelicobacter activity of these luminally acting agents is not as well understood.”
“Presumably, tetracycline had formed extracellular chelation complexes with calcium , thus accounting for the pigmentation of the conjunctiva.”
“To the Editor.— Concerning the interaction of antibiotics with other drugs (219:206, 1972), Kabins is correct in stating that gastrointestinal binding of tetracycline with polyvalent cations (aluminum, calcium , and magnesium) may decrease the absorption of the antibiotic.”
“At a tetracycline concentration of only 10 ~g/ml the uptake of calcium was significantly lowered.”
The effect of tetracycline and oxytetracycline on the formation of biological apatite“ Comme la tétracycline ne se combine pas avec le calcium des statolithes de sulfate de calcium dihydraté d'Aurelia, l'explication des effets d'inhibition sur la différenciation de statolithes et nématocystes ne semble pas liée avec un facteur en rapport avec l'incorporation.”
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