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Last Updated: 3 years ago

Possible Interaction: Tempol and Vitamin C

drug:

Tempol

supplement:

Vitamin C

Research Papers that Mention the Interaction

In vitro studies showed that TEMPOL was reduced rapidly by ascorbic acid but not by reduced glutathione.
Investigative ophthalmology & visual science  •  1998  |  View Paper
The primary reductant was identified as reduced ascorbic acid, and the rate of reduction of tanol correlated directly with the concentrations of ascorbic acid in the various muscle extracts as shown by chemical analysis.
Proceedings of the National Academy of Sciences of the United States of America  •  1980  |  View Paper
One of the endogenous antioxidants, ascorbic acid , was significantly increased in the plasma of mice which consumed tempol.
Journal of clinical biochemistry and nutrition  •  2014  |  View Paper
In liposomal membranes, a synergistic effect was observed in the combination of nitroxyl radical I with ascorbic acid, whereas only an additive effect was observed between Tempol and ascorbic acid.
Lipids  •  2003  |  View Paper