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“ Tedisamil inhibits Ito, potassium current (IK), KATP and the protein kinase A-activated chloride channel in ventricles as well as vascular IK and Ca2+ -activated IK (IK(Ca)).”
Expert opinion on investigational drugs • 2001 | View Paper
“Following recent findings it was hypothesized that defibrillating effect of tedisamil is likely due to its sympathomimetic feature linked with modulation of intracellular calcium.”