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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Taurine
drug:
Deoxycholate
Research Papers that Mention the Interaction
“ DOC had measurable growth-retarding effects at concentrations as low as 15 microM, and lithocholate at 2 microM. The glycine and taurine conjugates of bile acids were significantly less effective inhibitors of growth, as was the sulfate conjugate of lithocholic acid.”
Effect of bile acids on the growth and differentiation of cultured human keratinocytes.“However, the increase of deoxycholic acid and its taurine conjugates may be a factor that leads to persistence of mucosal lesions.”
“Conversely, during the deoxycholate plus taurine experiments, the secretion of the major monoenoic PC species (i.e., 16:0-18:1) increased more than that of the polyenoic species.”
“ Taurine conjugates of chenodeoxycholate and deoxycholate , but not cholate and ursodeoxycholate, inhibited the CYP7A promoter/luciferase reporter activity in transient transfection assays in Hep G2 cells.”
Identification of a bile acid response element in the cholesterol 7 alpha-hydroxylase gene CYP7A.
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