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Last Updated: 2 years ago

Possible Interaction: Taurine and Chenodeoxycholate

supplement:

Taurine

Research Papers that Mention the Interaction

The primary dihydroxy bile acid, chenodeoxycholate , was more toxic at high concentrations than at low concentrations, but conjugation with taurine reversed it.
Advances in experimental medicine and biology  •  1987  |  View Paper
Taurine conjugates of chenodeoxycholate and deoxycholate, but not cholate and ursodeoxycholate, inhibited the CYP7A promoter/luciferase reporter activity in transient transfection assays in Hep G2 cells.
The American journal of physiology  •  1997  |  View Paper
The formation of chenodeoxycholyl-D-cystenolic acid was decreased by the addition of various concentrations of taurine to the incubation mixture.
Biological & pharmaceutical bulletin  •  1993  |  View Paper
Conjugation of either lithocholate or chenodeoxycholate with either glycine or taurine markedly reduced the ability of the bile salt to enhance O2- release from primed PMNs.
Toxicology and applied pharmacology  •  1988  |  View Paper
Pretreatment for 3 days with taurine 0.5% in drinking water led to a 70% increase of the SRm for chenodeoxycholic acid.
Pediatric Research  •  1988  |  View Paper
Taurine and glycine conjugates of chenodeoxycholic acid were more active inhibitors than were the cholic acid conjugates.
American journal of surgery  •  1974  |  View Paper
The concentration of taurine conjugates of cholic acid … of both groups was similar, but concentration of taurine conjugates … chenodeoxycholic acid in bile of low responding animals was higher than in high responding animals (124.9 +/- ….3 in low vs. 59.2 +/- 13.2 &mgr;mol/ml in high responders).
The Journal of nutritional biochemistry  •  2001  |  View Paper