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Discover Supplement-Drug Interactions

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Last Updated: 6 months ago

Possible Interaction: Taurine and Becaplermin



Research Papers that Mention the Interaction

Previously, we demonstrated that taurine significantly suppressed PDGF-BB-induced cell proliferation, DNA synthesis, immediate-early gene expressions and extracellular signal-regulated kinase (ERK) 1/2 phosphorylation in VSMCs.
We showed that taurine significantly suppressed PDGF-BB-induced phosphorylation of PDGF-beta receptor and activation of its downstream signaling molecules such as Ras, MAPK/ERK kinase (MEK)1/2 and Akt.
Biochimica et biophysica acta  •  2005  |  View Paper
Taurine inhibited PDGF-BB-induced c-fos and c-jun mRNA expressions dose-dependently, although structural analogues of taurine did not.
Journal of nutritional science and vitaminology  •  2003  |  View Paper
Taurine markedly increased the synthesis of cAMP and suppressed the gene expression of c-jun and c-fos (P<0.01) in addition to the inhibition of the proliferative effect of platelet-derived growth factor BB on HSC.
Hepatobiliary & pancreatic diseases international : HBPD INT  •  2004  |  View Paper