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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“ Ascorbic acid inhibited the mutation frequency (80-90%) of N-hydroxyphenacetin in both TA 100 and TA 98 and of p-nitrosophenetole in TA 100 but caused a slight increase in the mutation frequency of N-hydroxy-2-aminofluorene and 2-nitrosofluorene in both TA 98 and TA 100.”
Mechanism of N-hydroxyacetylarylamine mutagenicity in the Salmonella test system: metabolic activation of N-hydroxyphenacetin by liver and kidney fractions from rat, mouse, hamster, and man.“We … that TA had a profound dose-dependent inhibitory effect upon Cu(2+)-catalysed ascorbic acid oxidation (monitored by O2 uptake and spectrophotometrically at 265 nm) and also increased the partition of Cu2+ into n-octanol from an aqueous solution suggesting that TA forms a lipophilic complex with Cu2+.”
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