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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Tannins
supplement:
Iron, Dietary
Research Papers that Mention the Interaction
“Treatment with TA (Fe:TA molar ratio of 1:1) significantly decreased Fe bioavailability (about 97 %) from both FeSO4 and the ferritin samples.”
Effects of ascorbic acid, phytic acid and tannic acid on iron bioavailability from reconstituted ferritin measured by an in vitro digestion–Caco-2 cell model“Iron dialyzability decreased when iron was mixed with CaCl2 and phytic or tannic acid (T test p < 0.0001, for both) but not when mixed with pectin.”
“We report a case of glossal pigmentation similar to black hairy tongue, caused by uptake of iron and tannins.”
“Adding phytic acid (10:1) and tannic acid (1:1) to iron decreased iron bioavailability from SFP by 91 and 99%, respectively.”
“Also, the tannic acid present in St. John’s Wort may prevent absorption of iron , an important mineral for pregnant women and their babies.”
“ TA and fish decreased total Fe solubility.”
“Also, the tannic acid present in St. John’s Wort may prevent absorption of iron , an important mineral for pregnant women and their babies.”
“ Tannic acids present in some herbs (eg, St John wort and saw palmetto) may inhibit the absorption of iron.”
“ Tannic acid has a much greater relative binding efficiency to iron than propyl gallate, methyl gallate or gallic acid.”
“The phenolic compounds (phenolic monomers, polyphenols, tannins ) are considered to interfere with iron absorption by complex formation with iron in the gastro-intestinal lumen, making the iron less available for absorption.”
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