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Last Updated: 2 months ago

Possible Interaction: Tamoxifen and Taurine



Research Papers that Mention the Interaction

Most importantly, pharmacological blockade of swelling-activated taurine efflux by tamoxifen or NPPB caused proliferating cervical cancer cells to arrest in G0/G1, suggesting that the activity of this efflux was associated with G1/S checkpoint progression.
Pflügers Archiv  •  2000  |  View Paper
The results indicated that taurine pre-treatment showed significant increment in the levels of GSH content, reduction in DNA fragmentation and ladder formation in hepatic tissue, suggesting the antioxidant activity of taurine may reduce the toxic effects of MTX and TAM.
Environmental toxicology and pharmacology  •  2011  |  View Paper
The typical VRAC blockers, NPPB, IAA‐94, and tamoxifen blocked low divalent cation‐induced glutamate and taurine release and LY loading, presumed due to hemichannel opening.
Glia  •  2009  |  View Paper
The present study was undertaken to investigate modulatory effects of taurine on the nephrotoxicity of TAM with special reference to protection against disruption of nonenzymatic and enzymatic antioxidants.
Human & experimental toxicology  •  2007  |  View Paper
Moreover, in rats treated with tamoxifen the concentration of bile acids conjugated with taurine significantly increased.
Pharmacological reports : PR  •  2006  |  View Paper
Topically applied anion channel blockers 4,4′-diisothiocyanatostilbene-2,2′-disulfonic acid (1 mM); 4-acetamido-4′-isothiocyanatostilbene-… acid (2 mM); 5-nitro-2-(3-phenylpropylamino) benzoic acid (350 μM); niflumic acid (500 μM); tamoxifen (20 μM) and arachidonic acid (0.5 … reduced the hyposmotically-induced release of taurine.
Neurochemical Research  •  2004  |  View Paper
Tamoxifen (20 microM in artificial cerebrospinal fluid), applied topically, inhibited the ischemia-evoked efflux of aspartate, glutamate, taurine and phosphoethanolamine.
Brain Research  •  1998  |  View Paper