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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Tamoxifen and Lignans

supplement:

Lignans

Research Papers that Mention the Interaction

Ten percent FS and equivalent lignans do not interfere with but rather increase the effectiveness of tamoxifen (80 mg/day) while the 4% FS oil increases trastuzumab/Herceptin (2.5 mg/kg) effectiveness.
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme  •  2014  |  View Paper
ED and EL at doses of 0.1–10 µM reduced cell migration, but TAM had no effect … 0.1 and 1 µM, and exhibited a stimulatory effect at 10 µM. It is concluded that lignans … TAM , alone or in combination, can inhibit … steps involved in the metastasis cascade.
Breast Cancer Research and Treatment  •  2004  |  View Paper