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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
Research Papers that Mention the Interaction
“Results: Four of the herbals tested, echinacea, ginseng , lemon balm, and skullcap, were found to be strong inhibitors of the CYP450 enzymatic bioactivation pathways of TAM with IC50 values as percent of a single dose ranging from 0.019% to 0.34%.”
In vitro inhibitory effects of herbal supplements on tamoxifen and irinotecan metabolism“In another paper titled “The Prescription Pattern of Chinese Herbal Products Containing Ginseng among Tamoxifen-Treated Female Breast Cancer Survivors in Taiwan: A Population-Based Study,” W.-L. Hsu et al. investigate the inhibitory relationship between Ginseng consumption and subsequent endometrial cancer among tamoxifen users.”
“Three papers are related to breast cancer risk of commonly used Chinese herbs; one of them considers the breast cancer risk of Chinese herbal remedies among hormone users, while another covers the subsequent endometrial cancer problems when tamoxifen users consume Ginseng.”
Integrative Gynecology and Women's Healthcare“A significant inhibitory relationship between Ginseng consumption and subsequent endometrial cancer less than 2 years after TMX treatment was detected among BC survivors.”
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