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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Tamoxifen and Echinacea

supplement:

Echinacea

Research Papers that Mention the Interaction

Results: Four of the herbals tested, echinacea , ginseng, lemon balm, and skullcap, were found to be strong inhibitors of the CYP450 enzymatic bioactivation pathways of TAM with IC50 values as percent of a single dose ranging from 0.019% to 0.34%.
Drug metabolism and drug interactions  •  2014  |  View Paper
We identified use of 35 different types of CAM products and seven of these could potentially increase the risk of breast cancer or interact with tamoxifen or aromatase inhibitors: soy, garlic, ginko biloba, echinacea , ginseng, valerian and phytoestrogens (excluding soy).
Lakartidningen  •  2005  |  View Paper