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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Tamoxifen
supplement:
Alpha-Tocopherol Acetate
Research Papers that Mention the Interaction
“BACKGROUND Vitamin E alpha-tocopherol acetate , AT) diminishes the antiproliferative effect of tamoxifen on breast cancer cells in vitro.”
“Either alpha-T or alpha-TAc increases membrane packing and prevents TAM partition into model membranes.”
“The hemolytic effect of TAM is prevented by low concentrations of alpha-tocopherol (alpha-T) and alpha-tocopherol acetate (alpha-TAc) (inactivated functional hydroxyl) indicating that TAM-induced hemolysis is not related to oxidative membrane damage.”
Hemolysis of human erythrocytes induced by tamoxifen is related to disruption of membrane structure.
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