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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Tamoxifen
supplement:
3-Nitrotyrosine
Research Papers that Mention the Interaction
“The … tamoxifen estrogen receptor modulator (10-7) into the cardio- and neurocyte incubation medium did not affect Klotho protein concentration (… in concentration of 34% and 28% respectively) in advanced cell suspensions as much as vitamin D, however, nitrotyrosine concentration decrease made a more expressed … average by 52% and 60%.”
THE IMPACT OF THE CHEMICAL AGENTS OF DIFFERENT PHARMACOLOGICAL GROUPS ON THE KLOTHO PROTEIN CONCENTRATION IN THE CARDIOMYOCYTE AND NEUROCYTE SUSPENSION IN 120 MINUTE HYPOXIA IN VITRO.“Compared with vehicle, TAM significantly reduced nitrotyrosine levels in the ischemic cortex at 24 h. The neuronal (n)NOS inhibitor, 7‐nitroindazole also tended to reduce nitrotyrosine, but this reduction was not statistically significant.”
“Immunostaining for nitrotyrosine was seen in cortical neurons in the MCA territory and this immunostaining was reduced by TAM.”
Tamoxifen inhibits nitrotyrosine formation after reversible middle cerebral artery occlusion in the rat
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