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Discover Supplement-Drug Interactions

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Possible Interaction: Tacrine and Alpha-Tocopherol Succinate

Research Papers that Mention the Interaction

In conclusion, our experimental data indicate that TS and CS are potent inhibitors of AChE activity and significantly potentiate the anticholinesterase activity of THA.
Results from these studies indicate that: [1] THA is a potent inhibitor of acetylcholinesterase (AChE, IC50 of 0.40 microM) and butyrylcholinesterase (BChE, IC50 … 100 microM and 168 microM, respectively) but potent inhibitors of ACHE (IC50 of 1.73 microM and 0.79 microM, respectively); [3] both TS … THA ….
Biochimica et biophysica acta  •  1994  |  View Paper