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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Suramin
supplement:
Polypeptides
Research Papers that Mention the Interaction
“These results are at variance … others recently reported, where suramin has been shown to … microaggregation of several polypeptides (Middaugh, C. R., Mach, H., Burke, C. J., Volkin, D. B., Dabora, J. M., Tsai, P. …., Bruner, M. W., Ryan, J. A., and Marfia, K. E. (1992) Biochemistry 31, 9016-9024).”
Suramin induces deoligomerization of human tumor necrosis factor alpha.“ Suramin is also found to inhibit protein synthesis affecting both initiation and elongation of the polypeptide chain.”
Suramin ameliorates collagen induced arthritis.“The inhibitory effect of suramin on the phosphorylation of GST-HBV core fusion protein (GST-Hcore) and two GST-Hcore fusion polypeptides (Hcore157B and Hcore164B) by two alpha-type cAMP-dependent protein kinases (PKAIalpha and PKAIIalpha) was biochemically investigated in vitro.”
Biochemical characterization of suramin as a selective inhibitor for the PKA-mediated phosphorylation of HBV core protein in vitro.
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