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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Suramin
supplement:
Iron, Dietary
Research Papers that Mention the Interaction
“ Suramin , a compound that has been used to treat metastatic prostate cancer, has been demonstrated to antagonize the binding of transferrin to the transferrin receptor and to suppress uptake of iron by hematopoietic cells.”
Reversal by transferrin of growth-inhibitory effect of suramin on hormone-refractory human prostate cancer cells.“ Suramin suppressed cell surface transferrin (Tf) binding and uptake of iron via inhibition of receptor-mediated endocytosis (RME).”
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